Cargando...

Structural insights into the targeting of mRNA GU-rich elements by the three RRMs of CELF1

The CUG-BP, Elav-like family (CELF) of RNA-binding proteins control gene expression at a number of different levels by regulating pre-mRNA splicing, deadenylation and mRNA stability. We present structural insights into the binding selectivity of CELF member 1 (CELF1) for GU-rich mRNA target sequence...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Edwards, John M., Long, Jed, de Moor, Cornelia H., Emsley, Jonas, Searle, Mark S.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2013
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3737555/
https://ncbi.nlm.nih.gov/pubmed/23748565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt470
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!