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Coordinate Regulation of mRNA Decay Networks by GU-rich Elements and CELF1
The GU-rich element (GRE) was identified as a conserved sequence enriched in the 3′ UTR of human transcripts that exhibited rapid mRNA turnover. In mammalian cells, binding to GREs by the protein CELF1 coordinates mRNA decay of networks of transcripts involved in cell growth, migration, and apoptosi...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3146975/ https://ncbi.nlm.nih.gov/pubmed/21497082 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2011.03.002 |
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