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Conserved GU-Rich Elements Mediate mRNA Decay by Binding to CUG-Binding Protein 1
We used computational algorithms to find conserved sequences in the 3′ untranslated region (UTR) of transcripts that exhibited rapid decay in primary human T cells and found that the consensus sequence UGUUUGUUUGU, which we have termed a GU-rich element (GRE), was enriched in short-lived transcripts...
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| Auteurs principaux: | , , , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2367162/ https://ncbi.nlm.nih.gov/pubmed/18243120 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.11.024 |
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