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Coordinate Regulation of mRNA Decay Networks by GU-rich Elements and CELF1

The GU-rich element (GRE) was identified as a conserved sequence enriched in the 3′ UTR of human transcripts that exhibited rapid mRNA turnover. In mammalian cells, binding to GREs by the protein CELF1 coordinates mRNA decay of networks of transcripts involved in cell growth, migration, and apoptosi...

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Hlavní autoři: Louis, Irina Vlasova-St., Bohjanen, Paul R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3146975/
https://ncbi.nlm.nih.gov/pubmed/21497082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2011.03.002
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