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Structural insights into the targeting of mRNA GU-rich elements by the three RRMs of CELF1
The CUG-BP, Elav-like family (CELF) of RNA-binding proteins control gene expression at a number of different levels by regulating pre-mRNA splicing, deadenylation and mRNA stability. We present structural insights into the binding selectivity of CELF member 1 (CELF1) for GU-rich mRNA target sequence...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3737555/ https://ncbi.nlm.nih.gov/pubmed/23748565 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt470 |
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