The antimicrobial peptide cathelicidin modulates Clostridium difficile-associated colitis and toxin A-mediated enteritis in mice

BACKGROUND: Clostridium difficile mediates intestinal inflammation by releasing toxin A (TxA), a potent enterotoxin. Cathelicidins (Camp as gene name, LL-37 peptide in humans and mCRAMP peptide in mice) are antibacterial peptides that also posses anti-inflammatory properties. OBJECTIVES: To determin...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Hing, Tressia C, Ho, Samantha, Shih, David Q, Ichikawa, Ryan, Cheng, Michelle, Chen, Jeremy, Chen, Xinhua, Law, Ivy, Najarian, Robert, Kelly, Ciaran P, Gallo, Richard L, Targan, Stephan R, Pothoulakis, Charalabos, Koon, Hon Wai
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3737259/
https://ncbi.nlm.nih.gov/pubmed/22760006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2012-302180
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