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The chromatin remodelling complex NoRC safeguards genome stability by heterochromatin formation at telomeres and centromeres

Constitutive heterochromatin is crucial for the integrity of chromosomes and genomic stability. Here, we show that the chromatin remodelling complex NoRC, known to silence a fraction of rRNA genes, also establishes a repressive heterochromatic structure at centromeres and telomeres, preserving the s...

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Detaylı Bibliyografya
Asıl Yazarlar: Postepska-Igielska, Anna, Krunic, Damir, Schmitt, Nina, Greulich-Bode, Karin M, Boukamp, Petra, Grummt, Ingrid
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: European Molecular Biology Organization 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3736129/
https://ncbi.nlm.nih.gov/pubmed/23797874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2013.87
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