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The chromatin remodelling complex NoRC safeguards genome stability by heterochromatin formation at telomeres and centromeres
Constitutive heterochromatin is crucial for the integrity of chromosomes and genomic stability. Here, we show that the chromatin remodelling complex NoRC, known to silence a fraction of rRNA genes, also establishes a repressive heterochromatic structure at centromeres and telomeres, preserving the s...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
European Molecular Biology Organization
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3736129/ https://ncbi.nlm.nih.gov/pubmed/23797874 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2013.87 |
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