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The NoRC complex mediates the heterochromatin formation and stability of silent rRNA genes and centromeric repeats
Maintenance of specific heterochromatic domains is crucial for genome stability. In eukaryotic cells, a fraction of the tandem-repeated ribosomal RNA (rRNA) genes is organized in the heterochromatic structures. The principal determinant of rDNA silencing is the nucleolar remodelling complex, NoRC, t...
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| Hoofdauteurs: | , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group
2010
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2905252/ https://ncbi.nlm.nih.gov/pubmed/20168299 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.17 |
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