The chromatin remodelling complex NoRC safeguards genome stability by heterochromatin formation at telomeres and centromeres

Constitutive heterochromatin is crucial for the integrity of chromosomes and genomic stability. Here, we show that the chromatin remodelling complex NoRC, known to silence a fraction of rRNA genes, also establishes a repressive heterochromatic structure at centromeres and telomeres, preserving the s...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Postepska-Igielska, Anna, Krunic, Damir, Schmitt, Nina, Greulich-Bode, Karin M, Boukamp, Petra, Grummt, Ingrid
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: European Molecular Biology Organization 2013
Gaiak:
Scientific Reports
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3736129/
https://ncbi.nlm.nih.gov/pubmed/23797874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2013.87
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