LDL particle core enrichment in cholesteryl oleate increases proteoglycan binding and promotes atherosclerosis

Several studies in humans and animals suggest that LDL particle core enrichment in cholesteryl oleate (CO) is associated with increased atherosclerosis. Diet enrichment with MUFAs enhances LDL CO content. Steroyl O-acyltransferase 2 (SOAT2) is the enzyme that catalyzes the synthesis of much of the C...

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Main Authors: Melchior, John T., Sawyer, Janet K., Kelley, Kathryn L., Shah, Ramesh, Wilson, Martha D., Hantgan, Roy R., Rudel, Lawrence L.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Biochemistry and Molecular Biology 2013
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3735946/
https://ncbi.nlm.nih.gov/pubmed/23804810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M039644
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