LDL particle core enrichment in cholesteryl oleate increases proteoglycan binding and promotes atherosclerosis

Several studies in humans and animals suggest that LDL particle core enrichment in cholesteryl oleate (CO) is associated with increased atherosclerosis. Diet enrichment with MUFAs enhances LDL CO content. Steroyl O-acyltransferase 2 (SOAT2) is the enzyme that catalyzes the synthesis of much of the C...

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Autori principali: Melchior, John T., Sawyer, Janet K., Kelley, Kathryn L., Shah, Ramesh, Wilson, Martha D., Hantgan, Roy R., Rudel, Lawrence L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Biochemistry and Molecular Biology 2013
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3735946/
https://ncbi.nlm.nih.gov/pubmed/23804810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M039644
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