LDL particle core enrichment in cholesteryl oleate increases proteoglycan binding and promotes atherosclerosis

Several studies in humans and animals suggest that LDL particle core enrichment in cholesteryl oleate (CO) is associated with increased atherosclerosis. Diet enrichment with MUFAs enhances LDL CO content. Steroyl O-acyltransferase 2 (SOAT2) is the enzyme that catalyzes the synthesis of much of the C...

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Autors principals: Melchior, John T., Sawyer, Janet K., Kelley, Kathryn L., Shah, Ramesh, Wilson, Martha D., Hantgan, Roy R., Rudel, Lawrence L.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Biochemistry and Molecular Biology 2013
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3735946/
https://ncbi.nlm.nih.gov/pubmed/23804810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M039644
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