To trim or not to trim: Progression and control of DSB end resection

DNA double-strand breaks (DSBs) are the most cytotoxic form of DNA damage, since they can lead to genome instability and chromosome rearrangements, which are hallmarks of cancer cells. To face this kind of lesion, eukaryotic cells developed two alternative repair pathways, homologous recombination (...

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Detaylı Bibliyografya
Asıl Yazarlar: Granata, Magda, Panigada, Davide, Galati, Elena, Lazzaro, Federico, Pellicioli, Achille, Plevani, Paolo, Muzi-Falconi, Marco
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Landes Bioscience 2013
Konular:
Perspective
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3735699/
https://ncbi.nlm.nih.gov/pubmed/23708517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.25042
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