Histone methyltransferase Dot1 and Rad9 inhibit single-stranded DNA accumulation at DSBs and uncapped telomeres

Cells respond to DNA double-strand breaks (DSBs) and uncapped telomeres by recruiting checkpoint and repair factors to the site of lesions. Single-stranded DNA (ssDNA) is an important intermediate in the repair of DSBs and is produced also at uncapped telomeres. Here, we provide evidence that bindin...

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Bibliografski detalji
Glavni autori: Lazzaro, Federico, Sapountzi, Vasileia, Granata, Magda, Pellicioli, Achille, Vaze, Moreshwar, Haber, James E, Plevani, Paolo, Lydall, David, Muzi-Falconi, Marco
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2008
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2328446/
https://ncbi.nlm.nih.gov/pubmed/18418382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.81
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