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To trim or not to trim: Progression and control of DSB end resection

DNA double-strand breaks (DSBs) are the most cytotoxic form of DNA damage, since they can lead to genome instability and chromosome rearrangements, which are hallmarks of cancer cells. To face this kind of lesion, eukaryotic cells developed two alternative repair pathways, homologous recombination (...

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Bibliografski detalji
Glavni autori: Granata, Magda, Panigada, Davide, Galati, Elena, Lazzaro, Federico, Pellicioli, Achille, Plevani, Paolo, Muzi-Falconi, Marco
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3735699/
https://ncbi.nlm.nih.gov/pubmed/23708517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.25042
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