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To trim or not to trim: Progression and control of DSB end resection
DNA double-strand breaks (DSBs) are the most cytotoxic form of DNA damage, since they can lead to genome instability and chromosome rearrangements, which are hallmarks of cancer cells. To face this kind of lesion, eukaryotic cells developed two alternative repair pathways, homologous recombination (...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Landes Bioscience
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3735699/ https://ncbi.nlm.nih.gov/pubmed/23708517 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.25042 |
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