Yeast Rad52 and Rad51 Recombination Proteins Define a Second Pathway of DNA Damage Assessment in Response to a Single Double-Strand Break

Saccharomyces cells with a single unrepaired double-strand break adapt after checkpoint-mediated G(2)/M arrest. We have found that both Rad51 and Rad52 recombination proteins play key roles in adaptation. Cells lacking Rad51p fail to adapt, but deleting RAD52 suppresses rad51Δ. rad52Δ also suppresse...

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Detalhes bibliográficos
Main Authors: Lee, Sang Eun, Pellicioli, Achille, Vaze, Moreshwar B., Sugawara, Neal, Malkova, Anna, Foiani, Marco, Haber, James E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC262690/
https://ncbi.nlm.nih.gov/pubmed/14612428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.23.8913-8923.2003
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