Saccharomyces CDK1 Phosphorylates Rad53 Kinase in Metaphase, Influencing Cellular Morphogenesis

Rad53 is an essential protein kinase governing DNA damage and replication stress checkpoints in budding yeast. It also appears to be involved in cellular morphogenesis processes. Mass spectrometry analyses revealed that Rad53 is phosphorylated at multiple SQ/TQ and at SP/TP residues, which are typic...

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Autores principales: Diani, Laura, Colombelli, Claudia, Nachimuthu, Benjamin Tamilselvan, Donnianni, Roberto, Plevani, Paolo, Muzi-Falconi, Marco, Pellicioli, Achille
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2009
Materias:
Mechanisms of Signal Transduction
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781677/
https://ncbi.nlm.nih.gov/pubmed/19801655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.048157
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