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Mechanism of Dun1 Activation by Rad53 Phosphorylation in Saccharomyces cerevisiae
Despite extensive studies, the molecular mechanism of DNA damage checkpoint activation remains incompletely understood. To better dissect this mechanism, we developed an activity-based assay for Dun1, a downstream DNA damage checkpoint kinase in yeast, using its physiological substrate Sml1. Using t...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2006
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2811688/ https://ncbi.nlm.nih.gov/pubmed/17114794 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M609322200 |
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