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Mechanism of Dun1 Activation by Rad53 Phosphorylation in Saccharomyces cerevisiae
Despite extensive studies, the molecular mechanism of DNA damage checkpoint activation remains incompletely understood. To better dissect this mechanism, we developed an activity-based assay for Dun1, a downstream DNA damage checkpoint kinase in yeast, using its physiological substrate Sml1. Using t...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2811688/ https://ncbi.nlm.nih.gov/pubmed/17114794 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M609322200 |
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