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Structural mechanism for affinity maturation of an anti-lysozyme antibody
In the immune response against a typical T cell-dependent protein antigen, the affinity maturation process is fast and is associated with the early class switch from IgM to IgG. As such, a comprehension of the molecular basis of affinity maturation could be of great importance in biomedical and biot...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2004
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC373498/ https://ncbi.nlm.nih.gov/pubmed/14988501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0400060101 |
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