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Structural mechanism for affinity maturation of an anti-lysozyme antibody

In the immune response against a typical T cell-dependent protein antigen, the affinity maturation process is fast and is associated with the early class switch from IgM to IgG. As such, a comprehension of the molecular basis of affinity maturation could be of great importance in biomedical and biot...

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Detalhes bibliográficos
Main Authors: Cauerhff, Ana, Goldbaum, Fernando A., Braden, Bradford C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC373498/
https://ncbi.nlm.nih.gov/pubmed/14988501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0400060101
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