Determination of detection and quantification limits for SNP allele frequency estimation in DNA pools using real time PCR

The quantification of single nucleotide polymorphism (SNP) allele frequencies in pooled DNA samples using real time PCR is a promising approach for large-scale diagnostics and genotyping. The limits of detection (LOD) and limits of quantification (LOQ) for mutant SNP alleles are of particular import...

Full beskrivning

Bibliografiska uppgifter

I publikationen:	Nucleic Acids Res
Huvudupphov:	Schwarz, Gerhard, Bäumler, Stefan, Block, Annette, Felsenstein, Friedrich G., Wenzel, Gerhard
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	Oxford University Press 2004
Ämnen:	NAR Methods Online
Länkar:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC373417/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14960708/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gnh020
Taggar:	Lägg till en tagg Inga taggar, Lägg till första taggen!