Determination of detection and quantification limits for SNP allele frequency estimation in DNA pools using real time PCR

The quantification of single nucleotide polymorphism (SNP) allele frequencies in pooled DNA samples using real time PCR is a promising approach for large-scale diagnostics and genotyping. The limits of detection (LOD) and limits of quantification (LOQ) for mutant SNP alleles are of particular import...

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Dades bibliogràfiques

Publicat a:	Nucleic Acids Res
Autors principals:	Schwarz, Gerhard, Bäumler, Stefan, Block, Annette, Felsenstein, Friedrich G., Wenzel, Gerhard
Format:	Artigo
Idioma:	Inglês
Publicat:	Oxford University Press 2004
Matèries:	NAR Methods Online
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC373417/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14960708/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gnh020
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