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Determination of detection and quantification limits for SNP allele frequency estimation in DNA pools using real time PCR

The quantification of single nucleotide polymorphism (SNP) allele frequencies in pooled DNA samples using real time PCR is a promising approach for large-scale diagnostics and genotyping. The limits of detection (LOD) and limits of quantification (LOQ) for mutant SNP alleles are of particular import...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Schwarz, Gerhard, Bäumler, Stefan, Block, Annette, Felsenstein, Friedrich G., Wenzel, Gerhard
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2004
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC373417/
https://ncbi.nlm.nih.gov/pubmed/14960708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gnh020
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