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Determination of detection and quantification limits for SNP allele frequency estimation in DNA pools using real time PCR
The quantification of single nucleotide polymorphism (SNP) allele frequencies in pooled DNA samples using real time PCR is a promising approach for large-scale diagnostics and genotyping. The limits of detection (LOD) and limits of quantification (LOQ) for mutant SNP alleles are of particular import...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2004
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC373417/ https://ncbi.nlm.nih.gov/pubmed/14960708 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gnh020 |
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