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Determination of detection and quantification limits for SNP allele frequency estimation in DNA pools using real time PCR

The quantification of single nucleotide polymorphism (SNP) allele frequencies in pooled DNA samples using real time PCR is a promising approach for large-scale diagnostics and genotyping. The limits of detection (LOD) and limits of quantification (LOQ) for mutant SNP alleles are of particular import...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nucleic Acids Res
Prif Awduron: Schwarz, Gerhard, Bäumler, Stefan, Block, Annette, Felsenstein, Friedrich G., Wenzel, Gerhard
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2004
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC373417/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14960708/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gnh020
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