Histone deacetylase inhibition in the treatment of acute myeloid leukemia: the effects of valproic acid on leukemic cells, and the clinical and experimental evidence for combining valproic acid with other antileukemic agents

Several new therapeutic strategies are now considered for acute myeloid leukemia (AML) patients unfit for intensive chemotherapy, including modulation of protein lysine acetylation through inhibition of histone deacetylases (HDACs). These enzymes alter the acetylation of several proteins, including...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Fredly, Hanne, Gjertsen, Bjørn Tore, Bruserud, Øystein
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2013
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3733883/
https://ncbi.nlm.nih.gov/pubmed/23898968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1868-7083-5-12
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker