Disease-stabilizing treatment based on all-trans retinoic acid and valproic acid in acute myeloid leukemia – identification of responders by gene expression profiling of pretreatment leukemic cells

BACKGROUND: Acute myeloid leukemia (AML) is an aggressive malignancy only cured by intensive therapy. However, many elderly and unfit patients cannot receive such treatment due to an unacceptable risk of treatment-related morbidity and mortality. Disease-stabilizing therapy is then the only possible...

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Publicat a:BMC Cancer
Autors principals: Reikvam, Håkon, Hovland, Randi, Forthun, Rakel Brendsdal, Erdal, Sigrid, Gjertsen, Bjørn Tore, Fredly, Hanne, Bruserud, Øystein
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5586053/
https://ncbi.nlm.nih.gov/pubmed/28877686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3620-y
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