Llwytho...

Histone deacetylase inhibition in the treatment of acute myeloid leukemia: the effects of valproic acid on leukemic cells, and the clinical and experimental evidence for combining valproic acid with other antileukemic agents

Several new therapeutic strategies are now considered for acute myeloid leukemia (AML) patients unfit for intensive chemotherapy, including modulation of protein lysine acetylation through inhibition of histone deacetylases (HDACs). These enzymes alter the acetylation of several proteins, including...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Fredly, Hanne, Gjertsen, Bjørn Tore, Bruserud, Øystein
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3733883/
https://ncbi.nlm.nih.gov/pubmed/23898968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1868-7083-5-12
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