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A genetic screen identifies TCF3/E2A and TRIAP1 as pathway-specific regulators of the cellular response to p53 activation
The p53 transcription factor participates in diverse cellular responses to stress including cell cycle arrest, apoptosis, senescence and autophagy. The molecular mechanisms defining the ultimate outcome to p53 activation remain poorly characterized. We performed a genome-wide genetic screen in human...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3733554/ https://ncbi.nlm.nih.gov/pubmed/23684607 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.04.014 |
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