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Targeting Alzheimer's disease genes with RNA interference: an efficient strategy for silencing mutant alleles
Tau and amyloid precursor protein (APP) are key proteins in the pathogenesis of sporadic and inherited Alzheimer’s disease. Thus, developing ways to inhibit production of these proteins is of great research and therapeutic interest. The selective silencing of mutant alleles, moreover, represents an...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2004
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC373334/ https://ncbi.nlm.nih.gov/pubmed/14754988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh208 |
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