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A novel assay to determine the sequence preference and affinity of DNA minor groove binding compounds
Sequence-specific binding in the minor groove of DNA by small molecules is a growing area of research with possible therapeutic relevance. By selectively binding to DNA sequences required by critical transcription factors, these small molecules could potentially modulate the expression levels of dis...
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| Foilsithe in: | Nucleic Acids Res |
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| Main Authors: | , , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
Oxford University Press
2004
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC373301/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14718553/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gng155 |
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