A novel assay to determine the sequence preference and affinity of DNA minor groove binding compounds

Sequence-specific binding in the minor groove of DNA by small molecules is a growing area of research with possible therapeutic relevance. By selectively binding to DNA sequences required by critical transcription factors, these small molecules could potentially modulate the expression levels of dis...

Fuld beskrivelse

Bibliografiske detaljer

Udgivet i:	Nucleic Acids Res
Principais autores:	Thomas, Rita, Gonzalez, Carolyn, Roberts, Christopher, Botyanszki, Janos, Lou, Lillian, Michelotti, Emil F.
Format:	Artigo
Sprog:	Inglês
Udgivet:	Oxford University Press 2004
Fag:	NAR Methods Online
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC373301/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14718553/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gng155
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