A novel assay to determine the sequence preference and affinity of DNA minor groove binding compounds

Sequence-specific binding in the minor groove of DNA by small molecules is a growing area of research with possible therapeutic relevance. By selectively binding to DNA sequences required by critical transcription factors, these small molecules could potentially modulate the expression levels of dis...

Täydet tiedot

Bibliografiset tiedot

Julkaisussa:	Nucleic Acids Res
Päätekijät:	Thomas, Rita, Gonzalez, Carolyn, Roberts, Christopher, Botyanszki, Janos, Lou, Lillian, Michelotti, Emil F.
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Oxford University Press 2004
Aiheet:	NAR Methods Online
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC373301/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14718553/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gng155
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