A novel assay to determine the sequence preference and affinity of DNA minor groove binding compounds

Sequence-specific binding in the minor groove of DNA by small molecules is a growing area of research with possible therapeutic relevance. By selectively binding to DNA sequences required by critical transcription factors, these small molecules could potentially modulate the expression levels of dis...

Descripción completa

Detalles Bibliográficos

Publicado en:	Nucleic Acids Res
Autores principales:	Thomas, Rita, Gonzalez, Carolyn, Roberts, Christopher, Botyanszki, Janos, Lou, Lillian, Michelotti, Emil F.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Oxford University Press 2004
Materias:	NAR Methods Online
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC373301/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14718553/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gng155
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!