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Sequence-specific minor groove binding by bis-benzimidazoles: water molecules in ligand recognition

The binding of two symmetric bis-benzimidazole compounds, 2,2-bis-[4′-(3″-dimethylamino-1″-propyloxy)phenyl]-5,5-bi-1H-benzimidazole and its piperidinpropylphenyl analog, to the minor groove of DNA, have been studied by DNA footprinting, surface plasmon resonance (SPR) methods and molecular dynamics...

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Bibliografische gegevens
Hoofdauteurs: Bailly, Christian, Chessari, Gianni, Carrasco, Carolina, Joubert, Alexandra, Mann, John, Wilson, W. David, Neidle, Stephen
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2003
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC149830/
https://ncbi.nlm.nih.gov/pubmed/12595560
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