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Variability in DNA minor groove width recognised by ligand binding: the crystal structure of a bis-benzimidazole compound bound to the DNA duplex d(CGCGAATTCGCG)2.

An analogue of the DNA-binding compound Hoechst 33258, in which the piperazine ring has been replaced by an imidazoline group, has been cocrystallized with the dodecanucleotide sequence d(CGCGAATTCGCG)2. The structure has been solved by X-ray diffraction analysis and has been refined to an R-factor...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Principais autores: Wood, A A, Nunn, C M, Czarny, A, Boykin, D W, Neidle, S
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 1995
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307265/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7478996/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/23.18.3678
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