Sequence-specific minor groove binding by bis-benzimidazoles: water molecules in ligand recognition

The binding of two symmetric bis-benzimidazole compounds, 2,2-bis-[4′-(3″-dimethylamino-1″-propyloxy)phenyl]-5,5-bi-1H-benzimidazole and its piperidinpropylphenyl analog, to the minor groove of DNA, have been studied by DNA footprinting, surface plasmon resonance (SPR) methods and molecular dynamics...

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Pubblicato in:	Nucleic Acids Res
Autori principali:	Bailly, Christian, Chessari, Gianni, Carrasco, Carolina, Joubert, Alexandra, Mann, John, Wilson, W. David, Neidle, Stephen
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Oxford University Press 2003
Soggetti:	Articles
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC149830/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12595560/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg237
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