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Function of the C-terminus of φ29 DNA polymerase in DNA and terminal protein binding

The thumb subdomain, located in various family B DNA polymerases in the C-terminal region, has been shown in their crystal structures to move upon binding of DNA, changing its conformation to nearly completely wrap around the DNA. It has therefore been involved in DNA binding. In agreement with this...

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Hlavní autoři: Truniger, Verónica, Lázaro, José M., Salas, Margarita
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC373294/
https://ncbi.nlm.nih.gov/pubmed/14729920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh184
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