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Function of the C-terminus of φ29 DNA polymerase in DNA and terminal protein binding

The thumb subdomain, located in various family B DNA polymerases in the C-terminal region, has been shown in their crystal structures to move upon binding of DNA, changing its conformation to nearly completely wrap around the DNA. It has therefore been involved in DNA binding. In agreement with this...

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Detalhes bibliográficos
Main Authors: Truniger, Verónica, Lázaro, José M., Salas, Margarita
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC373294/
https://ncbi.nlm.nih.gov/pubmed/14729920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh184
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