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Inhibition of NF-κB and Akt pathways by an antibody-avidin fusion protein sensitizes malignant B-cells to cisplatin-induced apoptosis

Multiple myeloma (MM) is an incurable disease of malignant plasma cells. Recent therapeutic advancements have resulted in improved response rates, however, there is no improvement in overall survival, therefore, new therapeutics are needed. Since the transferrin receptor is upregulated on the surfac...

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Autors principals: SUZUKI, ERIKO, DANIELS, TRACY R., HELGUERA, GUSTAVO, PENICHET, MANUEL L., UMEZAWA, KAZUO, BONAVIDA, BENJAMIN
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3732793/
https://ncbi.nlm.nih.gov/pubmed/20372806
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