Molecular events contributing to cell death in malignant human hematopoietic cells elicited by an IgG3-avidin fusion protein targeting the transferrin receptor

We have previously reported that an anti-human transferrin receptor IgG3-avidin fusion protein (anti-hTfR IgG3-Av) inhibits the proliferation of an erythroleukemia-cell line. We have now found that anti-hTfR IgG3-Av also inhibits the proliferation of additional human malignant B and plasma cells. An...

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Main Authors: Ng, Patrick P., Helguera, Gustavo, Daniels, Tracy R., Lomas, Simon Z., Rodriguez, Jose A., Schiller, Gary, Bonavida, Benjamin, Morrison, Sherie L., Penichet, Manuel L.
Formato: Artigo
Idioma:Inglês
Publicado: © 2006 by The American Society of Hematology 2006
Assuntos:
Neoplasia
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895578/
https://ncbi.nlm.nih.gov/pubmed/16804109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-04-020263
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