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An Antibody-based Multifaceted Approach Targeting the Human Transferrin Receptor for the Treatment of B-cell Malignancies

We previously developed an antibody-avidin fusion protein (ch128.1Av) targeting the human transferrin receptor 1 (TfR1, also known as CD71), which demonstrates direct in vitro cytotoxicity against malignant hematopoietic cells. This cytotoxicity is attributed to its ability to decrease the level of...

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Bibliografski detalji
Glavni autori: Daniels, Tracy R., Ortiz-Sánchez, Elizabeth, Luria-Pérez, Rosendo, Quintero, Rafaela, Helguera, Gustavo, Bonavida, Benjamin, Martínez-Maza, Otoniel, Penichet, Manuel L.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3717268/
https://ncbi.nlm.nih.gov/pubmed/21654517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0b013e318222ffc8
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