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Strategic targeting of the PI3K–NFκB axis in cisplatin-resistant NSCLC
Chemoresistance is a major therapeutic challenge to overcome in NSCLC, in order to improve the current survival rates of <15% at 5 years. We and others have shown increased PI3K signaling in NSCLC to be associated with a more aggressive disease, and a poorer prognosis. In this study, targeted inh...
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| Main Authors: | , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Landes Bioscience
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4130730/ https://ncbi.nlm.nih.gov/pubmed/25025901 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.29841 |
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