Targeting the cancer stem cell marker, aldehyde dehydrogenase 1, to circumvent cisplatin resistance in NSCLC

Non-small cell lung cancer (NSCLC) accounts for a large proportion of cancer deaths and is characterized by low treatment response rates and poor overall prognosis. In the absence of specific treatable mutations, cisplatin-based chemotherapy plays an important role in the treatment of this disease....

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: MacDonagh, Lauren, Gallagher, Michael F., Ffrench, Brendan, Gasch, Claudia, Breen, Eamon, Gray, Steven G., Nicholson, Siobhan, Leonard, Niamh, Ryan, Ronan, Young, Vincent, O'Leary, John J., Cuffe, Sinead, Finn, Stephen P., O'Byrne, Kenneth J., Barr, Martin P.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5641151/
https://ncbi.nlm.nih.gov/pubmed/29069808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19881
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