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Akt-mediated regulation of NFκB and the essentialness of NFκB for the oncogenicity of PI3K and Akt

The serine/threonine kinase Akt (cellular homolog of murine thymoma virus akt8 oncogene), also known as PKB (protein kinase B), is activated by lipid products of phosphatidylinositol 3-kinase (PI3K). Akt phosphorylates numerous protein targets that control cell survival, proliferation and motility....

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Detalhes bibliográficos
Main Authors: Bai, Dong, Ueno, Lynn, Vogt, Peter K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2767458/
https://ncbi.nlm.nih.gov/pubmed/19609947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.24748
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