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Akt-mediated regulation of NFκB and the essentialness of NFκB for the oncogenicity of PI3K and Akt
The serine/threonine kinase Akt (cellular homolog of murine thymoma virus akt8 oncogene), also known as PKB (protein kinase B), is activated by lipid products of phosphatidylinositol 3-kinase (PI3K). Akt phosphorylates numerous protein targets that control cell survival, proliferation and motility....
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2767458/ https://ncbi.nlm.nih.gov/pubmed/19609947 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.24748 |
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