Targeted Modifications in Adeno-Associated Virus Serotype 8 Capsid Improves Its Hepatic Gene Transfer Efficiency In Vivo

Recombinant adeno-associated virus vectors based on serotype 8 (AAV8) have shown significant promise for liver-directed gene therapy. However, to overcome the vector dose dependent immunotoxicity seen with AAV8 vectors, it is important to develop better AAV8 vectors that provide enhanced gene expres...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Sen, Dwaipayan, Gadkari, Rupali A, Sudha, Govindarajan, Gabriel, Nishanth, Kumar, Yesupatham Sathish, Selot, Ruchita, Samuel, Rekha, Rajalingam, Sumathi, Ramya, V., Nair, Sukesh C., Srinivasan, Narayanaswamy, Srivastava, Alok, Jayandharan, Giridhara R.
التنسيق: Artigo
اللغة:Inglês
منشور في: Mary Ann Liebert, Inc. 2013
الموضوعات:
Research Articles
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3732127/
https://ncbi.nlm.nih.gov/pubmed/23442071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hgtb.2012.195
الوسوم: إضافة وسم
لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!

مواد مشابهة