Adeno-Associated Virus Serotype 6 Capsid Tyrosine-to-Phenylalanine Mutations Improve Gene Transfer to Skeletal Muscle

Adeno-associated viral (AAV) vectors are the most efficient in vivo gene transfer tools for gene therapy applications. Efforts have been made to translate encouraging results in small animal models to human patients. However, the need for large quantities of vector for clinical application remains a...

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Detalhes bibliográficos
Main Authors: Qiao, Chunping, Zhang, Wei, Yuan, Zhenhua, Shin, Jin-Hong, Li, Jianbin, Jayandharan, Giridhara R., Zhong, Li, Srivastava, Arun, Xiao, Xiao, Duan, Dongsheng
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2010
Assuntos:
Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2957235/
https://ncbi.nlm.nih.gov/pubmed/20497037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2010.003
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