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Viral serotype and the transgene sequence influence overlapping adeno-associated viral (AAV) vector-mediated gene transfer in skeletal muscle

BACKGROUND: The overlapping approach was developed recently to expand the adeno-associated viral (AAV) packaging capacity. In this approach, a gene is split into two partially overlapping fragments and separately packaged into an upstream and a downstream vector, respectively. Transgene expression i...

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Detalhes bibliográficos
Main Authors: Ghosh, Arkasubhra, Yue, Yongping, Duan, Dongsheng
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2581716/
https://ncbi.nlm.nih.gov/pubmed/16385549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jgm.835
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