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Efficient Whole-body Transduction with Trans-splicing Adeno-associated Viral Vectors
Limited packaging capacity has hampered adeno-associated virus (AAV)-mediated gene therapy for many common genetic diseases such as cystic fibrosis (CF) and Duchenne muscular dystrophy (DMD). Trans-splicing AAV (tsAAV) vectors double AAV packaging capacity but their transduction efficiency has been...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2581720/ https://ncbi.nlm.nih.gov/pubmed/17264855 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.mt.6300081 |
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