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Efficient Whole-body Transduction with Trans-splicing Adeno-associated Viral Vectors

Limited packaging capacity has hampered adeno-associated virus (AAV)-mediated gene therapy for many common genetic diseases such as cystic fibrosis (CF) and Duchenne muscular dystrophy (DMD). Trans-splicing AAV (tsAAV) vectors double AAV packaging capacity but their transduction efficiency has been...

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Bibliografische gegevens
Hoofdauteurs: Ghosh, Arkasubhra, Yue, Yongping, Long, Chun, Bostick, Brian, Duan, Dongsheng
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2007
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2581720/
https://ncbi.nlm.nih.gov/pubmed/17264855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.mt.6300081
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